Juniper Publishers bioequivalence And bioavailability international journal

Biocorona: The Shadowed Side of Nanoparticles by Fabiola Porta in Modern Applications of Bioequivalence & Bioavailability | Juniper Publishers Under physiological conditions nanomaterials encounter a vast number of proteins in circulation. Those two dynamically interact with each other forming the so called biocorona. Accordingly, the biocorona is the layer of proteins in direct contact with the surface of nanomaterials, which may influence physical parameters of colloidal suspensions and thereby impact pharmacokinetics and dynamics of the formulated compound. Even though many experimental data have been gathered to understand the formation and the composition of the biocorona, the physiological impact of this protein layer is still a pristine area of research. The nature of the nanomaterials and the surface modifications performed to achieve controlled release of bioactive compounds influence thoroughly the nature of the biocorona. The focus of this review ...

Adaptive Quantum Computation in Changing Environments Using a Multi-Mimotopic Algorithmic Approach for Biclustering Analysis of Expression Data Projective Simulation on an Anticancer Peptide SVS-1 Multipharmacophore as a Potential Drug-Like Efficator in Preceding Membrane Neutralization by Nikolaos SG in Modern Applications of Bioequivalence & Bioavailability International Journal | Juniper Publishers Anticancer peptides (ACPs) are polycationic amphiphiles capable of preferentially killing a wide spectrum of cancer cells relative to non- cancerous cells. Their primary mode of action is an interaction with the cell membrane and subsequent activation of lyric effects however it remains controversial the exact mechanism responsible for this mode of action. It has in previous studies been shown that utilizing zeta potential analyses it was possible to demonstrate the interaction of a small anticancer peptide with membrane model systems and cancer cells. Electrosta...